Can vocal cord nodules turn into cancer?

Written by Xu Qing Tian
Otolaryngology
Updated on March 01, 2025
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Patients with vocal cord nodules usually do not undergo cancerous changes. The main causes of vocal cord nodules are related to improper use of the voice, excessive vocalization, and other factors. The pathological basis for the formation of vocal cord nodules involves edema in the Reinke's layer of the vocal cord mucosa, causing symmetrical hyperplasia of the vocal cords on both sides. The main symptoms in patients are hoarseness and difficulty in producing high-pitched sounds. The primary treatments for patients with vocal cord nodules currently include medication and surgery. Additionally, it is important for patients to protect their voice in daily life, practice voice rest, and reduce unhealthy habits like smoking and alcohol consumption to help prevent the occurrence of vocal cord nodules. (Medication should be used under the guidance of a doctor.)

Other Voices

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Written by Deng Bang Yu
Otolaryngology
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Can people with vocal cord nodules drink alcohol?

Vocal cord nodules are benign neoplasms located on the vocal cords, usually occurring bilaterally and symmetrically. The main clinical symptom is hoarseness. Individuals with vocal cord nodules should avoid alcohol, as drinking can cause the vocal cord mucosa to become congested and swollen, exacerbating vocal cord nodules or chronic inflammation, and worsening the condition. Additionally, alcohol can directly irritate the vocal cords because it is a spicy and irritating substance. Therefore, it is advised not to drink alcohol when you have vocal cord nodules. It is also important to avoid abusing the voice, which includes refraining from long periods of speaking and not screaming loudly. These precautions need to be adhered to.

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Written by Li Rui
Otolaryngology
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What should I do if the vocal cord nodules become fibrotic?

Vocal cord nodules fibrosis is relatively common. Firstly, it is necessary to visit an otolaryngology department for a laryngoscopy to assess the severity of the condition. If the symptoms of hoarseness are not very pronounced and the vocal cord nodules are small, it is recommended to rest the voice and avoid excessive use of the voice, with regular follow-ups. If the vocal cord nodules are larger and accompanied by hoarseness, it may be necessary to consider oral medication and nebulization treatment. During the treatment process, laryngoscopy should be repeatedly done to monitor changes in the nodules. A small number of patients may require surgical removal if conservative treatment does not yield satisfactory results.

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Written by Xu Qing Tian
Otolaryngology
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Dietary precautions for vocal cord nodules

Vocal cord nodules, also known as singer's nodules, are most commonly seen in professions such as teachers, singers, and speakers. These professions generally involve extensive use of the voice, which can lead to the development of bilateral symmetrical nodules on the vocal cords, primarily causing the patient to have a hoarse voice and difficulty continuing with their work. Treatment generally requires surgery, although milder cases may be treated with medication. During and after the treatment, whether surgical or medicinal, attention must be paid to certain lifestyle and dietary practices. Dietary precautions mainly involve avoiding spicy and irritating foods, as well as reducing smoking and alcohol consumption. In terms of lifestyle, it is important to minimize voice use as much as possible within the first month after surgery to avoid further strain on the vocal cords.

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Written by Zhang Jun
Otolaryngology
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Scraping therapy is effective for vocal cord nodules

Vocal cord nodules are ineffective with scraping therapy. Vocal cord nodules are bilateral vocal fold lesions caused by improper voice use over long periods, excessive strain, loud yelling, or irritation from gastric acid reflux. They can cause persistent hoarseness in the patient, progressively worsening over time. If a patient experiences long-term hoarseness without improvement, it is essential to undergo an examination with an electronic laryngoscope at a hospital. This can reveal a symmetrical, smooth-surfaced, protein-based abnormal growth at the anterior-middle third of both vocal cords, leading to incomplete closure of the vocal folds, which results in hoarseness. Treatment requires surgical intervention, as scraping therapy is ineffective. The procedure involves the removal of the vocal cord nodules under general anesthesia with a surgical laryngoscope. Post-surgery, antibiotics are used to prevent local infection and recovery is typically within about a week for hospital discharge.

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Written by Li Mao Cai
Otolaryngology
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How to treat vocal cord nodules?

The main symptom of vocal cord nodules is a hoarse voice, and some people often experience coughing. The cause of vocal cord nodules is related to excessive talking or improper use of the voice, such as in occupations like teachers, salespeople, and singers. Besides voice therapy, another treatment option is nebulizer inhalation, which is used to alleviate symptoms. Commonly used medications include corticosteroids, such as budesonide for nebulizer inhalation treatment, twice a day, one dose each time, but voice therapy is a prerequisite. Without voice therapy and correct voice usage, treatment with medication alone through nebulizer inhalation will not be effective, and the symptoms will not improve significantly. Some patients with vocal cord nodules do not need medication and can fully recover their normal voice and have the nodules disappear just by proper voice therapy and resting the voice for a period. Therefore, voice therapy is the best treatment for this condition.