How can precocious puberty be treated? Is it reversible?

Written by Quan Xiang Mei
Pediatrics
Updated on September 01, 2024
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Precocious puberty has many causes, including genetic factors, conditions during the mother's pregnancy, or congenital pituitary abnormalities, all of which can lead to the condition. When precocious puberty occurs, it is necessary to conduct diagnostic tests including MRI of the pituitary in the head, bone age assessment, ultrasonography of the gonads, and blood hormone level measurements to determine the appropriate treatment. Mild cases can be managed through a balanced diet, appropriate exercise, and rest. In some cases, oral Chinese medicine can be used if blood hormone levels are not severe enough to require other treatments, to help control the child’s sexual development. In severe cases, such as when a child's bone age is more than one year above their actual age, accompanied by abnormal blood hormone levels and changes in gonadal ultrasound, and significant loss in height, it may be necessary to administer injections of gonadotropin-releasing hormone analogs to control the level of sexual development. If there is a significant loss in height, it may also be necessary to combine this with growth hormone injections to treat growth.

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Written by Dong Xian Yan
Pediatrics
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Does precocious puberty require growth hormone treatment?

For children with precocious puberty, a small number require combined treatment with growth hormones. For instance, if a child's height growth rate is less than 4cm, it is necessary to add growth hormones to promote growth and development. The second scenario involves using a bone age test; if the height is less than 151cm, growth hormones can also be used in combination for treatment. In the third scenario, if the child's bone age at the time of consultation has already exceeded 11.5 years, has significantly increased, or even if menstruation has started and their height has been clearly affected, it is generally advised to use growth hormones in combination with treatment.

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Written by Quan Xiang Mei
Pediatrics
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Premature breast pain has now stopped hurting, does that mean it's healed?

When girls develop breasts before the age of eight, they may experience pain at the breast bud nodules. Pain does not necessarily mean recovery; it is possible that as the breast bud enlarges, the pain will naturally disappear. Whether treatment is needed once precocious puberty occurs and whether it has reached a level of cure mainly depends on the assessment through pediatric bone age, gonadal ultrasound examinations, or a combination of brain pituitary MRI and blood hormone levels to analyze the severity of the condition. For mild cases, with appropriate medication, diet, and exercise guidance, children can reach a basic level of clinical cure. Severe cases require the control of the child's sexual development through the injection of gonadal hormones or hormone-releasing analogues. Psychological impacts due to early sexual development may also necessitate behavioral and psychological interventions.

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Written by Quan Xiang Mei
Pediatrics
1min 21sec home-news-image

How can precocious puberty be treated? Is it reversible?

Precocious puberty has many causes, including genetic factors, conditions during the mother's pregnancy, or congenital pituitary abnormalities, all of which can lead to the condition. When precocious puberty occurs, it is necessary to conduct diagnostic tests including MRI of the pituitary in the head, bone age assessment, ultrasonography of the gonads, and blood hormone level measurements to determine the appropriate treatment. Mild cases can be managed through a balanced diet, appropriate exercise, and rest. In some cases, oral Chinese medicine can be used if blood hormone levels are not severe enough to require other treatments, to help control the child’s sexual development. In severe cases, such as when a child's bone age is more than one year above their actual age, accompanied by abnormal blood hormone levels and changes in gonadal ultrasound, and significant loss in height, it may be necessary to administer injections of gonadotropin-releasing hormone analogs to control the level of sexual development. If there is a significant loss in height, it may also be necessary to combine this with growth hormone injections to treat growth.

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Written by Yan Xin Liang
Pediatrics
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Will babies drinking soy milk lead to precocious puberty?

Soy milk is a rather nutritious food, containing rich plant protein and phospholipids, as well as vitamins B1, B2, and folic acid. Additionally, it contains iron, calcium, minerals, and other nutrients, making it an exceptional source of nutrition for children. It is generally fine for babies to drink soy milk in moderation as it can supplement various nutrients in the body. However, it should not be consumed in excess, as some studies have indicated that excessive consumption of soy milk could lead to pseudoprecocious puberty, which refers to early breast development. But, this is only pseudoprecocity, so there is no need for excessive worry. At the same time, attention should also be paid to other aspects of the diet, such as not consuming too many beverages and avoiding out-of-season vegetables.

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Written by Zeng Hai Jiang
Pediatrics
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What should I do if precocious puberty is not treated in time?

Precocious puberty is defined as the abnormal condition where secondary sexual characteristics develop before the age of eight in girls and nine in boys. The harm of this disease includes shorter adult height, earlier sexual behavior, and suppressed personality, among other effects. The principle of treatment primarily focuses on improving the child's adult height, with treatments mainly including medication and etiological treatment. If diagnosed and treated early, the prognosis is generally good, and the final adult height can be significantly improved. If treatment is not administered in a timely manner, and the epiphyses of the bones have closed, it may not be possible to alter the final height.