Infertility examinations typically include physical exams and special tests. Physical exams mainly involve checking the development of internal and external reproductive organs and secondary sexual characteristics. Special tests can include examining the quality of male semen, endocrine conditions, and anti-sperm antibodies. Additional procedures can include scrotal ultrasound, prostate ultrasound, prostate massage fluid analysis, and monitoring of the spermatic veins with ultrasound to check for varicoceles.

For females, it is important to check for any underlying diseases and ensure normal development of the uterus, ovaries, and adnexa. Examinations should also check for uterine fibroids, ovarian cysts, and endometriomas, and assess for any abnormalities in the reproductive tract. Monitoring ovulation is also crucial to identify any abnormalities in ovulation. If ovulation is normal, the patency of the fallopian tubes should be checked, which can be done through a fallopian tube iodine contrast imaging procedure.