Anal fistulas secondary to which disease?

Written by Chen Tian Jing
Colorectal Surgery
Updated on November 06, 2024
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An anal fistula generally originates from a perianal abscess, which is an infection focus formed near the anal sinuses in the local area of the anus. During its onset, there is obvious local redness, swelling, heat, and pain accompanied by the formation of a pus cavity containing pus. As the condition of the perianal abscess worsens, the local pus cavity will rupture and discharge pus, thus forming an anal fistula. After the rupture of a perianal abscess, its external opening cannot heal by itself, and there will be intermittent recurring discharge of pus. Therefore, it is necessary to carry out surgical treatment as soon as possible after the formation of an anal fistula, to prevent the enlargement of the local pus cavity or thickening of the fistula wall, which complicates later surgery and treatment and significantly impacts the patient's normal life.

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Written by Chen Tian Jing
Colorectal Surgery
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Does an anal fistula hurt?

Anal fistula mainly refers to the presence of a noticeable fistula in the tissue under the perianal skin, which connects the inner opening in the anal canal and the outer opening around the anus. Usually, the anal fistula does not cause significant pain when it is not in acute flare-up. However, if the anal fistula enters an acute episode, there may be pain due to inflammation at the local external opening of the anus, and possibly an increase in purulent discharge, which can irritate the skin around the external opening, causing stinging pain and itching. To prevent recurrent episodes of anal fistula and further aggravation of the condition, it is advised to seek surgery as soon as the fistula is detected.

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Written by Yang Dong
Colorectal Surgery Department
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Anal fistula etiology

The cause of an anal fistula is due to infection of the anal glands. In normal human anatomy, there is a location at the junction of the rectum and the anal canal called the anal sinus or anal gland, which is relatively weak. If it is damaged, intestinal bacteria can enter the anal gland, causing inflammation. Over time, the infected anal gland leads to further abscesses towards the perianal space, causing a perianal abscess. After the perianal abscess ruptures, it further develops into an anal fistula.

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Written by Chen Tian Jing
Colorectal Surgery
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Symptoms of cancerous transformation in anal fistula

The vast majority of anal fistulas do not undergo malignant transformation. However, there is a possibility of cancerous changes if an anal fistula that has repeatedly recurred over a long period is not treated aggressively, or if the inflammation of the fistula tract is severe. When an anal fistula undergoes malignant transformation, the secretion from the local fistula tract increases and is accompanied by a foul smell, and there may even be ulceration of the local fistula tract mucosa. Further surgical procedures, such as fistulotomy with seton placement, are required, and the excised fistula tract suspected of high-grade malignant transformation should be sent for pathological examination. If malignant transformation is confirmed, further pelvic MRI examinations are necessary to determine whether there is local and surrounding lymph node metastasis.

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Written by Yu Xu Chao
Colorectal Surgery
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How to determine if you have an anal fistula

First, you can judge whether you have an anal fistula based on symptoms. Patients with anal fistula often experience recurrent perianal swelling and pain, as well as discharge of pus and blood, which may also have a foul odor, with secretion often found on their underwear. In such cases, patients should consider whether they have an anal fistula. Additionally, patients with anal fistulas in the early stages often have perianal abscesses, which generally tend to form fistulas after the abscess ruptures spontaneously or is surgically drained. Patients can also visit the colorectal surgery department of a hospital for a digital rectal examination, where the fistula tract and the internal opening can be felt. MRI scans of the perianal region can also be performed to determine the type and severity of the anal fistula. Clinically, once an anal fistula is detected, it is advisable to opt for fistula excision surgery to completely cure the anal fistula by removing the internal opening and the fistula tract. Post-surgery, it is essential to persist with dressing changes to avoid wound infection and bleeding.

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Written by Chen Tian Jing
Colorectal Surgery
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Is anal fistula prone to recurrence?

If active anal fistulotomy and thread-drawing surgery are carried out after the onset of an anal fistula, it generally does not recur easily. However, if patients do not pay attention to good dietary and defecation habits after being discharged, it may lead to the reoccurrence of the anal fistula. This is because there are multiple anal crypts within the anal canal, and removing the local anal crypts during this episode does not guarantee that other anal crypts will not become inflamed or infected in the future. Especially when patients consume excessive amounts of chili peppers or alcohol, or when they experience diarrhea, it can potentially trigger another infection of the anal crypts. Therefore, to prevent recurrence of anal fistulas, it is necessary to cultivate good defecation and dietary habits to avoid the reoccurrence of anal fistulas.