Acute appendicitis pathological classification

Written by Ren Zheng Xin
Gastroenterology
Updated on June 29, 2025
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There are four main pathological types of acute appendicitis. The first is acute simple appendicitis, where symptoms are relatively mild, characterized only by small ulcers and bleeding spots on the mucosal surface. The second is acute suppurative appendicitis, with more severe symptoms including serosal congestion and purulent exudation. The third is gangrenous and perforating appendicitis, which progresses from suppurative appendicitis causing necrosis and perforation of the appendix wall, potentially leading to acute peritonitis. The fourth type is periappendiceal abscess, which results from the suppurative and gangrenous progression of acute appendicitis, with the greater omentum encapsulating the appendix, forming a severe mass or a periappendiceal abscess.

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Can appendicitis cause vomiting?

Some patients with appendicitis may experience symptoms such as nausea and vomiting. This is because the appendix is located in the lower right abdomen near the ileocecal area, and the appendix cavity is connected to the cecum. The appendix is an independent organ of the human digestive tract. When inflamed, the inflammation can easily irritate the surrounding intestines, causing intestinal spasms and contractions, leading to nausea and vomiting. A typical manifestation of appendicitis is referred pain in the lower right abdomen. Once appendicitis is diagnosed, it is advisable to promptly start anti-inflammatory treatment and, if necessary, proceed with surgical treatment. Appendicitis can range from acute simple appendicitis, which responds well to conservative anti-inflammatory treatment, to acute suppurative or even perforated appendicitis. In these severe cases, it is recommended to perform surgery as soon as possible to remove the appendix and clear the inflammatory secretions, alongside anti-inflammatory treatment.

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Written by Ren Zheng Xin
Gastroenterology
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Does acute appendicitis cause diarrhea?

Acute appendicitis rarely involves diarrhea. Typical symptoms include abdominal pain that begins around the navel or upper abdomen and gradually shifts to the lower right abdomen. The pain is persistent and localized. Additionally, irritation of the gastrointestinal tract may cause nausea or vomiting. If the appendix becomes suppurative or perforated, it can lead to tension in the abdominal muscles, tenderness, and rebound pain. Most cases of acute appendicitis require surgical removal, and currently, laparoscopic appendectomy is a commonly used procedure.

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Written by Ren Zheng Xin
Gastroenterology
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What tests are done for appendicitis?

Appendicitis examination primarily involves a physical examination. The patient lies flat with their legs bent, and the doctor stands on the patient's right side. The patient exposes their abdomen, and the doctor places their right palm flat in the middle of the abdomen, then smoothly performs a clockwise palpation, pressing the abdomen to check for rebound tenderness, especially at McBurney's point. If there is significant tenderness and rebound pain at McBurney's point, along with symptoms of fever and nausea, appendicitis is generally considered. An ultrasound can also be used as an auxiliary examination, where swelling of the appendix can be observed. Based on the physical examination and auxiliary tests, a preliminary diagnosis of appendicitis can be made.

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General Surgery
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Early symptoms of appendicitis

What are the initial symptoms of appendicitis? It is characterized by abdominal pain. The main symptom is abdominal pain that appears around the upper abdomen or navel, and some patients may also experience nausea and vomiting. Generally, two to three hours later, the abdominal pain gradually shifts to the lower right abdomen, which we clinically refer to as migratory right lower abdominal pain. This symptom accounts for about 80% of clinical cases, while some patients present directly with pain in the lower right abdomen, without transitional abdominal pain. Therefore, the primary symptom of appendicitis is abdominal pain, as described in these two scenarios. However, physical examination is also very important, typically revealing localized fixed tenderness in the lower right abdomen as the main clinical manifestation.

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Written by Li Jin Quan
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Is chronic appendicitis serious?

Chronic appendicitis can achieve good treatment outcomes through active surgical treatment or conservative treatment, and the cases of appendicitis here are not severe. However, a very small portion of patients with chronic appendicitis, especially those with underlying diseases such as diabetes, are at risk of developing a purulent infection of the appendix, which can lead to perforation of the appendix and result in diffuse peritonitis, sepsis, septic shock, and multiple organ failure. Thus, it can be said that there are indeed a few severe cases among patients with chronic appendicitis.