Can Helicobacter pylori tests be done during the pregnancy preparation stage?

Written by Qu Chun Yao
Obstetrics and Gynecology
Updated on January 18, 2025
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During the preconception stage, it is possible to test for Helicobacter pylori, but if testing is to be conducted, breath tests should be avoided. This is because breath tests use carbon-14 or carbon-13, which are radioactive, making them unsuitable for women planning pregnancy.

At this time, it is also important to weigh the pros and cons. If there are chronic gastric or duodenal ulcers, and the symptoms are quite apparent, it is necessary to conduct tests. It is advisable to postpone pregnancy, address the gastrointestinal diseases first, and then proceed with pregnancy. If there are gastric or duodenal diseases at such time, pregnancy could possibly exacerbate the condition.

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Written by Si Li Li
Gastroenterology
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How to treat Helicobacter pylori infection?

Helicobacter pylori has been confirmed as a major cause of chronic gastritis, peptic ulcers, and even gastric cancer. The infection rate of Helicobacter pylori in China is very high, exceeding 50%. It is related to the dietary structure in China, often linked significantly to the practice of sharing dishes during meals, which correlates with China's dietary habits. If someone tests positive for Helicobacter pylori and has symptoms of gastrointestinal disorders, such as indigestion, stomach pain, or bloating, then it is necessary to undergo treatment for Helicobacter pylori. The current standard treatment for Helicobacter pylori involves quadruple therapy: a proton pump inhibitor, two types of antibiotics, and a bismuth agent. This combination of medications is administered over a period of 14 days, representing the standardized treatment for Helicobacter pylori.

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Written by Si Li Li
Gastroenterology
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Does a positive Helicobacter pylori require treatment?

Currently, the infection rate of Helicobacter pylori in our country has exceeded 50%. If there is an infection of Helicobacter pylori and it is accompanied by symptoms or diseases of the digestive system, or if the patient has a family history of gastric cancer, eradication treatment for Helicobacter pylori is needed. This is because Helicobacter pylori has been proven to be the main cause of chronic gastritis, peptic ulcers, and even gastric cancer. The method of eradication involves a proton pump inhibitor, two types of antibiotics, and a bismuth agent, with treatment lasting for 14 days. After the 14-day treatment period, medications are stopped for a month. One month later, a carbon-14 breath test is performed to confirm whether Helicobacter pylori has been converted to negative. If it has converted to negative, it means that the eradication treatment was successful.

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Written by Wu Hai Wu
Gastroenterology
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Is Helicobacter pylori a serious illness?

Helicobacter pylori is not a major disease, so patients do not need to be overly anxious and worried. Once an infection of Helicobacter pylori is detected, patients can consider visiting the gastroenterology department of a formal hospital. The choice of medication should be based on the doctor's experience. Also, the use and dosage of the medication should be followed according to the doctor's instructions. For the treatment of Helicobacter pylori infections, it is recommended to use a bismuth-containing quadruple therapy for two weeks to eradicate the infection. During the treatment period, it is advisable to avoid eating spicy and irritating foods, and also to avoid alcohol, strong tea, coffee, etc. Avoid overeating and eat small, easily digestible meals more frequently. (Please follow the doctor’s prescription when using medication.)

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Written by Si Li Li
Gastroenterology
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Is Helicobacter pylori three pluses serious?

Three pluses for Helicobacter pylori indicate that there is an infection with Helicobacter pylori, and the level of infection is not low. Helicobacter pylori is the main cause of chronic gastritis, peptic ulcers, and even stomach cancer. If a person tests positive for Helicobacter pylori infection, and has symptoms or diseases related to the digestive system, or has a family history of stomach cancer, eradication treatment for Helicobacter pylori is necessary. The treatment involves a proton pump inhibitor plus two types of antibiotics, along with a bismuth agent, for a total of 14 days. After stopping the medication for one month, a carbon-14 breath test should be re-conducted. If the result turns negative, it means that the eradication treatment for Helicobacter pylori was successful. If it does not turn negative, remedial treatment is required.

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Written by Yang Chun Guang
Gastroenterology
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Can a gastroscopy detect Helicobacter pylori?

Helicobacter pylori is a type of bacterium that can easily infect and cause chronic gastritis, and it even has the potential to lead to cancer. Therefore, patients with Helicobacter pylori generally require formal treatment. In terms of diagnostics, Helicobacter pylori can be detected through a gastroscopy, but the bacteria cannot be detected by gastroscopy alone; the test for Helicobacter pylori is performed under the scope. However, the current main method for testing Helicobacter pylori is through a breath test, since undergoing a gastroscopy just to test for the bacteria can be quite uncomfortable. Moreover, the accuracy of the breath test is relatively high, so currently, Helicobacter pylori is generally detected via breath testing rather than gastroscopy.