What should I do if I feel uncomfortable in my stomach and intestines after treatment for Helicobacter pylori?

Written by Wu Hai Wu
Gastroenterology
Updated on February 26, 2025
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The main reason for discomfort in the stomach and intestines after treatment for Helicobacter pylori might very likely be due to the consumption of clarithromycin, metronidazole, etc., as metronidazole, clarithromycin, and others can also irritate the gastrointestinal tract. Therefore, it is recommended to take metronidazole, clarithromycin, and other similar medications about half an hour after meals to reduce their side effects. If the patient experiences gastrointestinal discomfort, consider using medications that regulate the gut flora for treatment, such as compounded lactobacillus, bifidobacterium triple live bacteria, and bacillus coagulans, etc.

If the stomach discomfort is quite severe, medications that protect the gastric mucosa, such as magnesium trisilicate or vitamin B6, may be taken. These medications can help alleviate the side effects of other drugs and reduce symptoms of nausea and vomiting.

Discomfort might also be due to incomplete healing. First, it is necessary to return to a regular hospital for a follow-up consultation. If the symptoms have not worsened, it is important to continue taking the prescribed medications as advised by the doctor. Recent dietary habits should include eating regularly, having smaller, more frequent meals, and avoiding spicy, stimulating, and greasy foods. Rest should also be prioritized.

(Please follow medical advice when using medications.)

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Three pluses for Helicobacter pylori indicate that there is an infection with Helicobacter pylori, and the level of infection is not low. Helicobacter pylori is the main cause of chronic gastritis, peptic ulcers, and even stomach cancer. If a person tests positive for Helicobacter pylori infection, and has symptoms or diseases related to the digestive system, or has a family history of stomach cancer, eradication treatment for Helicobacter pylori is necessary. The treatment involves a proton pump inhibitor plus two types of antibiotics, along with a bismuth agent, for a total of 14 days. After stopping the medication for one month, a carbon-14 breath test should be re-conducted. If the result turns negative, it means that the eradication treatment for Helicobacter pylori was successful. If it does not turn negative, remedial treatment is required.

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Do you need to change your toothbrush when treating Helicobacter pylori?

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Symptoms of Helicobacter pylori infection

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