What should I do if I feel uncomfortable in my stomach and intestines after treatment for Helicobacter pylori?

Written by Wu Hai Wu
Gastroenterology
Updated on February 26, 2025
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The main reason for discomfort in the stomach and intestines after treatment for Helicobacter pylori might very likely be due to the consumption of clarithromycin, metronidazole, etc., as metronidazole, clarithromycin, and others can also irritate the gastrointestinal tract. Therefore, it is recommended to take metronidazole, clarithromycin, and other similar medications about half an hour after meals to reduce their side effects. If the patient experiences gastrointestinal discomfort, consider using medications that regulate the gut flora for treatment, such as compounded lactobacillus, bifidobacterium triple live bacteria, and bacillus coagulans, etc.

If the stomach discomfort is quite severe, medications that protect the gastric mucosa, such as magnesium trisilicate or vitamin B6, may be taken. These medications can help alleviate the side effects of other drugs and reduce symptoms of nausea and vomiting.

Discomfort might also be due to incomplete healing. First, it is necessary to return to a regular hospital for a follow-up consultation. If the symptoms have not worsened, it is important to continue taking the prescribed medications as advised by the doctor. Recent dietary habits should include eating regularly, having smaller, more frequent meals, and avoiding spicy, stimulating, and greasy foods. Rest should also be prioritized.

(Please follow medical advice when using medications.)

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Can I eat cake during the treatment of Helicobacter pylori?

During the treatment process for Helicobacter pylori, it is permissible to eat cake, as there are no specific dietary restrictions. However, it is important to avoid spicy and stimulating foods, as well as strong liquor, strong tea, coffee, etc. Treatment for Helicobacter pylori infection may include the use of proton pump inhibitors such as omeprazole and lansoprazole combined with antibiotics like amoxicillin, clarithromycin, and metronidazole, often in a quadruple therapy regimen with bismuth citrate for two weeks aimed at eradicating the infection. Patients with Helicobacter pylori infection should consume easy-to-digest, bland foods and avoid overly spicy and stimulating foods. (Please follow your doctor's prescription when using medications.)

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Does superficial gastritis infected with Helicobacter pylori need treatment?

Superficial gastritis, after infection with Helicobacter pylori, requires treatment. If not actively symptomatic treated, the condition can worsen and frequently relapse, increasing the risk of malignancy. For superficial gastritis with Helicobacter pylori, initial treatment can involve natural therapies to control and eradicate Helicobacter pylori completely. Subsequently, based on individual clinical symptoms, treatment should focus on chronic superficial gastritis. Regular maintenance primarily involves being cautious with diet, avoiding spicy foods, and refraining from consuming food that is too cold, too sweet, too hard, or too acidic, as well as overly stimulating foods.

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Can a gastroscopy detect Helicobacter pylori?

Since Helicobacter pylori is a type of bacterium, it cannot be seen with the naked eye. However, current research indicates that Helicobacter pylori is strongly associated with certain mucosal appearances under endoscopy. Therefore, endoscopists can infer the presence of an infection based on certain mucosal appearances observed during the procedure. However, if the only purpose is to test for Helicobacter pylori infection without needing a gastroscopy, then we can opt for non-invasive methods such as the carbon-13 urea breath test, carbon-14 urea breath test, stool antigen test, and serological antibody tests, which are commonly used methods of testing. Moreover, after treatment for Helicobacter pylori, it is recommended to use either the carbon-13 or carbon-14 urea breath test for examination.

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Can I take vitamins B1 and B12 during treatment for Helicobacter pylori?

During the treatment of Helicobacter pylori, it is possible to consume Vitamin B1 and Vitamin B12. The treatment of Helicobacter pylori infection can consider using a bismuth-containing quadruple therapy for two weeks to eradicate the infection. During the treatment of Helicobacter pylori infection, one can also eat fresh vegetables and fruits rich in vitamins, such as kiwis, bananas, apples, etc. It is important to eat regularly and in moderation, consume light, easily digestible foods, and avoid overeating. Spicy and stimulative foods should be avoided, including strong alcohol, strong tea, coffee, etc. At the same time, patients with Helicobacter pylori infection should also ensure adequate rest.

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Can treatment for Helicobacter pylori be stopped at any time?

During the treatment of Helicobacter pylori, it is not advisable to stop the medication arbitrarily, as doing so may lead to insufficient treatment duration and result in a failure to eradicate the bacteria. Therefore, it is recommended to use a bismuth-containing quadruple therapy for two weeks to eradicate Helicobacter pylori. The specific medications included in this two-week quadruple therapy are a proton pump inhibitor such as pantoprazole or lansoprazole, plus two antibiotics such as amoxicillin, clarithromycin, or metronidazole, combined with bismuth potassium citrate. The medication should be taken under medical supervision. Helicobacter pylori infection can be detected through a carbon-13 breath test or a carbon-14 breath test.