Mycoplasma infection is caused by the pathogen mycoplasma, an acute infection. Mycoplasma is a tiny microorganism that exists between bacteria and viruses, and it can affect multiple systems in the human body. For instance, it can invade the lungs, causing mycoplasma pneumonia, or affect the reproductive system, where in males it can cause prostatitis, and in females, vaginitis and cervicitis. Mycoplasma infections are somewhat contagious, thus it is crucial to treat them promptly. If considered as a genitourinary tract infection, both spouses should be treated together to fully cure the mycoplasma infection. The treatment often involves oral macrocyclic lactone antimicrobial drugs, typically over a course of two to three weeks. Besides the standardized use of medication, attention should be given to a light diet and personal hygiene practices.