Baby roseola and chickenpox have different manifestations. Roseola usually presents as small, bright red rashes, while chickenpox features small blisters in the center, about the size and shape of soybeans. If roseola is not severe, it can usually heal on its own after a while. However, chickenpox must be treated on schedule. When chickenpox is inflamed, small white blisters appear in the center. Another difference is that baby roseola is generally not easily infectious, but chickenpox can be spread through air and droplets.