Women with a septate uterus, if pregnant, are much more likely to experience premature birth compared to women with a normal uterus. The normal uterine cavity size accommodates the development of the embryo until full term. However, the likelihood of premature birth varies depending on the development of the septate uterus. Once diagnosed with a septate uterus, extra caution is needed during pregnancy, especially avoiding intercourse in the late stages of pregnancy to prevent premature birth, as the risks associated with preterm infants are significantly higher than those for full-term infants. Therefore, pregnant women with a septate uterus need to pay extra attention.