Do patients with tuberculosis have a runny nose? First, we need to understand what tuberculosis is. The pathogen of tuberculosis is Mycobacterium tuberculosis, commonly referred to as TB bacillus. Its primary site of infection is the lungs, but now we also classify and manage tracheobronchial and tuberculous pleurisy under pulmonary tuberculosis. However, these sites do not include the nasal part. Generally, patients with pulmonary tuberculosis show symptoms of the respiratory system and systemic symptoms. The most common respiratory symptoms include coughing and phlegm production for more than two weeks. Some patients may also experience hemoptysis, with varying amounts from mild to severe. A few patients may also experience chest pain. Additionally, patients with caseous pneumonia or significant pleural effusion may experience difficulty in breathing. Systemic symptoms of tuberculosis include fever, mainly characterized by afternoon tidal fever, with some patients exhibiting high fevers, and other general symptoms such as loss of appetite, weight loss, night sweats, and fatigue. However, the majority of patients with pulmonary tuberculosis do not exhibit nasal symptoms, meaning a runny nose is generally not a manifestation of tuberculosis. It could be possible that a tuberculosis patient might also have other infections or causative diseases, such as allergic rhinitis.