Precursors of renal failure

Written by Li Liu Sheng
Nephrology
Updated on April 25, 2025
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The kidneys have a very strong compensatory ability. When kidney function is slightly impaired, many people do not have any uncomfortable symptoms and feel everything is normal. However, if one actively seeks out early signs, it is possible to detect precursors to kidney failure. At this time, if one can go to the hospital in time for routine blood tests, urine tests, and kidney function tests, it is possible to determine if there is kidney failure. The most obvious precursor symptom of kidney failure is usually general fatigue, which many people tend to overlook. This is because there are indeed many reasons that can cause fatigue, especially since many people attribute it to fatigue or stress factors. Additionally, many patients with precursors to kidney failure experience edema, particularly the kind that disappears after rest, so it is especially not taken seriously. Another symptom of kidney failure precursors is a significant increase in the frequency of urination at night, which is also often overlooked.

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Chronic Renal Failure Treatment Plan

The treatment of chronic renal failure primarily requires a clear understanding of the cause, and treatment targeting the cause is essential to slow the progression of chronic renal failure. The most common causes of chronic renal failure are diabetes, hypertension, and chronic nephritis. Therefore, for patients with chronic renal failure caused by diabetes, insulin is often needed to control blood sugar. For patients with hypertensive kidney disease, antihypertensive drugs are certainly necessary to control blood pressure. However, in the early stages of renal failure, ACE inhibitors or ARBs are the preferred choices. For patients with chronic nephritis in the early stages, corticosteroid medications are required for treatment. However, if the serum creatinine has already exceeded 256 micromoles per liter, treatment then focuses mainly on managing complications, and corticosteroids are no longer used. (Please use medications under the guidance of a doctor.)

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Chronic kidney failure is not contagious.

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Chronic Renal Failure Clinical Manifestations

Patients with chronic renal failure may exhibit fatigue, which is mainly due to anemia. Patients with stage three or higher chronic renal failure generally have anemia, which can lead to symptoms such as fatigue, palpitations, and pallor. Additionally, patients may experience nausea and vomiting, which are primarily caused by an increase in toxins. Furthermore, patients may also exhibit symptoms such as edema and shortness of breath, as individuals with chronic renal failure typically experience reduced urine output. A higher intake than output over time can lead to an increased circulating blood volume, resulting in heart failure.