Chronic kidney failure generally may have some clinical symptoms, but many patients do not have any discomfort. Some common clinical symptoms mainly include increased urine foam and decreased urine output. Due to the decline in renal function for urine excretion, it can lead to edema, particularly in areas such as both ankles and the face. In the state of renal failure, patients may also experience hyperkalemia and metabolic acidosis. Due to metabolic acidosis, patients might exhibit deep and labored breathing. In the advanced stages of kidney failure, patients may suffer from renal anemia, leading to fatigue and potentially experiencing bone pain and susceptibility to fractures due to renal osteodystrophy.