Patients with chronic kidney failure should pay close attention to potential triggers that could worsen kidney failure. Avoiding or managing these triggers is crucial for slowing the progression of chronic kidney failure. Common causes include various factors that lead to renal ischemia and hypoxia, such as diarrhea, vomiting, and heat stroke in the summer. These factors can cause dehydration, leading to ischemia and hypoxia in the kidneys, which is a common scenario for the acute exacerbation of chronic kidney failure. Secondly, obstructions in the urinary system can also contribute to the progression of chronic kidney failure. For example, urinary system stones and benign prostatic hyperplasia in males can cause urinary obstruction, leading to further deterioration of kidney function. Finally, infections, heart failure, and hypercalcemia are also factors that can potentially worsen chronic kidney failure.