Can chronic renal failure be cured by dialysis?

Written by Zhou Qi
Nephrology
Updated on September 10, 2024
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Patients with chronic renal failure can undergo dialysis treatment to sustain life and improve quality of life. However, dialysis merely uses artificial means to excrete accumulated metabolic wastes and fluids in the body, regulate the internal environment, and simply substitutes for the function of the kidneys. Dialysis has no therapeutic value for renal failure itself. Therefore, patients with chronic renal failure should not expect dialysis to restore kidney function. Nonetheless, as a renal replacement therapy, dialysis can provide patients with a relatively good lifespan and quality of life. Dialysis treatment is necessary for patients with uremia.

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Written by Zhou Qi
Nephrology
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How to test for chronic renal failure?

The examinations for patients with chronic kidney failure are divided into several aspects: First, it is necessary to confirm the presence of chronic kidney failure and assess its severity. This requires blood tests for kidney function, observing levels of blood creatinine and urea nitrogen, and performing endogenous creatinine clearance tests to determine the degree of kidney failure; Second, it is important to determine whether there are complications associated with kidney failure. Therefore, routine blood tests are necessary to check for renal anemia, blood pressure measurements to observe if there is renal hypertension, and blood tests for electrolytes to check for any electrolyte disorders. These patients also need to have their parathyroid hormone levels checked and undergo iron metabolism tests to provide a basis for further treatment.

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Written by Zhou Qi
Nephrology
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Does chronic renal failure require dialysis?

Not all cases of chronic renal failure require dialysis. It is only considered when chronic renal failure progresses to an advanced stage, causing severe consequences, and the kidneys are unable to maintain normal body functions, leading to many complications. Generally, when chronic renal failure progresses to its final stage, i.e., uremia, the kidney function is left with about 10% capacity. The body then experiences a disruption in its internal environment, including the accumulation of a large amount of metabolic waste, serious electrolyte disorders, and severe metabolic acidosis. It is at this point that dialysis is considered. In the early stages of chronic renal failure, dialysis is not necessary.

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Written by Zhou Qi
Nephrology
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What are the symptoms of chronic kidney failure?

The symptoms of chronic kidney failure are related to the severity of the condition; the more severe the kidney failure, the more symptoms the patient will have. In the early stages, patients may not feel uncomfortable or show any symptoms. Some patients may experience swelling in the lower limbs and facial area. Others may display clinical signs such as elevated blood pressure and visible blood in the urine. As kidney failure progresses and blood creatinine levels exceed 442 umol/L, patients may experience fatigue, which is due to renal anemia. Some patients may also experience a loss of appetite, nausea, vomiting, and other gastrointestinal symptoms.

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Written by Wu Ji
Nephrology
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Symptoms of chronic renal failure

The clinical symptoms of chronic renal failure vary at different stages. In the compensatory and early decompensatory stages of chronic renal failure, patients may experience no symptoms or only mild discomforts such as fatigue, back pain, and increased nocturia, while a few may suffer from reduced appetite, metabolic acidosis, and mild anemia. The main clinical symptoms include disorders of water, electrolyte, and acid-base balance, presenting metabolic acidosis, sodium retention or hypovolemia, or hyponatremia, along with hyperkalemia. Moreover, there are significant manifestations of excess phosphorus and calcium deficiency. Patients may also experience disruptions in the metabolism of proteins, carbohydrates, fats, and vitamins. Cardiovascular symptoms mainly include hypertension, left ventricular hypertrophy, heart failure, and uremic cardiomyopathy. Gastrointestinal symptoms can manifest as loss of appetite, nausea, and vomiting. Hematological manifestations may include renal anemia and a tendency to bleed.

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Written by Zhou Qi
Nephrology
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Chronic Renal Failure Treatment Plan

The treatment of chronic renal failure primarily requires a clear understanding of the cause, and treatment targeting the cause is essential to slow the progression of chronic renal failure. The most common causes of chronic renal failure are diabetes, hypertension, and chronic nephritis. Therefore, for patients with chronic renal failure caused by diabetes, insulin is often needed to control blood sugar. For patients with hypertensive kidney disease, antihypertensive drugs are certainly necessary to control blood pressure. However, in the early stages of renal failure, ACE inhibitors or ARBs are the preferred choices. For patients with chronic nephritis in the early stages, corticosteroid medications are required for treatment. However, if the serum creatinine has already exceeded 256 micromoles per liter, treatment then focuses mainly on managing complications, and corticosteroids are no longer used. (Please use medications under the guidance of a doctor.)