What medicine is used for chronic renal failure?

Written by Zhou Qi
Nephrology
Updated on September 27, 2024
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The treatment of chronic renal failure primarily requires identifying the cause and treating it accordingly. Chronic renal failure refers to the state in which various diseases damage the kidneys, leading to the destruction of kidney tissue and resulting in the kidneys' inability to adequately excrete metabolic waste, causing an accumulation of such wastes in the body. There are no medications that can directly affect the kidneys, regenerate kidney tissue, and restore kidney function. Currently, medicine cannot achieve this, and there are no specific drugs for the treatment. Therefore, the treatment of chronic renal failure focuses on treating the primary disease to slow the progression of renal failure. For example, chronic renal failure caused by diabetes necessitates the use of insulin to control blood sugar, while patients with hypertension need to use antihypertensive drugs.

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Written by Zhang Hui
Nephrology
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Chronic renal failure anemia treatment

Patients with chronic renal failure generally have anemia combined with stage three or above of chronic kidney disease (CKD). When the hemoglobin falls below 100 grams per liter, it is necessary to start treatment to correct anemia. At this point, relevant lab tests should be conducted to check for abnormalities in folate, vitamin B12, ferritin, and serum iron levels, and specific treatments should be administered accordingly. Treatments generally include iron supplements, erythropoiesis-stimulating agents, folate, and vitamin B12 to help correct anemia.

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Written by Zhou Qi
Nephrology
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Why does chronic renal failure cause vomiting?

Patients with chronic renal failure who experience vomiting generally indicates that their condition has become very severe. Typically, from stage four of chronic kidney disease onwards, a large amount of metabolic waste accumulates in the body, and patients may have severe metabolic acidosis, among other issues. These conditions can cause edema of the gastrointestinal mucosa, and these metabolic wastes can also irritate the gastrointestinal tract, leading to symptoms like nausea, vomiting, and loss of appetite. Of course, besides these reasons, other gastrointestinal diseases such as chronic gastritis, gastric ulcers, and even gastric cancer should also be ruled out.

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Written by Zhou Qi
Nephrology
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Chronic Renal Failure Treatment Plan

The treatment of chronic renal failure primarily requires a clear understanding of the cause, and treatment targeting the cause is essential to slow the progression of chronic renal failure. The most common causes of chronic renal failure are diabetes, hypertension, and chronic nephritis. Therefore, for patients with chronic renal failure caused by diabetes, insulin is often needed to control blood sugar. For patients with hypertensive kidney disease, antihypertensive drugs are certainly necessary to control blood pressure. However, in the early stages of renal failure, ACE inhibitors or ARBs are the preferred choices. For patients with chronic nephritis in the early stages, corticosteroid medications are required for treatment. However, if the serum creatinine has already exceeded 256 micromoles per liter, treatment then focuses mainly on managing complications, and corticosteroids are no longer used. (Please use medications under the guidance of a doctor.)

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Written by Zhou Qi
Nephrology
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Can chronic renal failure reproduce?

Patients with chronic renal failure, if they are male, can attempt to conceive under the guidance of a clinic doctor after discontinuing the use of medications that affect fertility; usually, there are no major issues for male patients. However, for female patients, attempting to get pregnant carries a significant risk because pregnancy increases the burden on all organs, including the kidneys, which can exacerbate kidney diseases, especially in cases like lupus nephritis. Nevertheless, not all patients with chronic renal failure are absolutely unable to conceive; some have successfully managed the risks associated with pregnancy. In such cases, it is necessary to weigh the pros and cons.

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Written by Zhou Qi
Nephrology
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Can patients with chronic renal failure have sexual intercourse?

Patients with chronic renal failure can have sexual intercourse, but there are prerequisites. Since sexual activity is physically demanding and requires adequate cardiopulmonary function, patients can engage in sexual activity if they do not experience chest tightness or shortness of breath and their blood pressure is well controlled. If there are no obvious symptoms of fatigue, difficulty breathing, or chest tightness during sexual activity, there should be no significant problems. However, since the patients have chronic renal failure, it is advisable to avoid conception unless prepared for pregnancy. Pregnancy can further burden the kidneys in female patients and potentially exacerbate chronic renal failure. Male patients with chronic renal failure may be taking medications that could affect sperm quality. Therefore, contraception should be practiced unless preparations have been made.