Patients with mitral valve stenosis and insufficiency are advised not to run, as running is an aerobic exercise that increases heart rate. This can lead to symptoms like palpitations, chest tightness, and difficulty breathing, which are indicative of the heart needing more oxygen supply. Moreover, running increases the heart rate, which in turn increases the myocardial oxygen consumption and is detrimental to health. Particularly, running with mitral valve insufficiency is very dangerous. It is recommended to rest primarily and avoid participating in sports, especially running, for the health of the patient.