Arteriosclerosis is divided into several stages.

Written by Zeng Wei Jie
Cardiology
Updated on September 28, 2024
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Arterial atherosclerosis sequentially manifests as three major types: lipid spots and stripes, atheromatous and fibrous atheromatous plaques, and complex lesions. According to the process of its occurrence and development, it can be subdivided into six types. The first type is lipid spots, which are small yellow spots on the arterial intima that gradually develop into the second type, lipid stripes, where some yellow stripes appear on the arterial intima. Then there is the third type, pre-lesional plaque, where more lipid droplets appear extracellularly. The fourth type is the atheromatous plaque, where lipids accumulate excessively and form lipid pools, and the intimal structure will be damaged. The fifth type is the fibrous atheromatous plaque, which is the most characteristic lesion of arterial atherosclerosis. The sixth type is a complex lesion, representing a severe condition.

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Written by Zeng Wei Jie
Cardiology
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The earliest lesions of arteriosclerosis

The earliest lesion of atherosclerosis is the formation of lipid spots and streaks. The so-called lipid spots are small yellow dots that appear on the arterial intima. Under pathological observation, these are small areas of macrophages containing lipid droplets, forming a cluster of foam cells. As this small yellow dot develops, it gradually turns into a yellow streak made up of layers of macrophages containing lipids. The intima also comprises smooth muscle cells and lipids, as well as an infiltration of T cells, resembling a yellow streak on the intima.

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Written by Zeng Wei Jie
Cardiology
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How is arteriosclerosis treated?

To treat arteriosclerosis, we differentiate treatments based on the severity of the condition. For early-stage patients, we emphasize the control of lipids, blood pressure, and blood sugar to potentially slow the progression of arteriosclerosis. For patients who have already suffered damage to target organs, such as cerebral infarction, myocardial infarction, renal artery stenosis, or mesenteric artery stenosis, treatment might significantly rely on medication, and could possibly require the use of stents or even surgical bypass procedures. For the general population, we emphasize primary prevention, which includes a reasonable diet, appropriate exercise, and a balanced mental state to effectively prevent the disease.

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Written by Zeng Wei Jie
Cardiology
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Risk factors for arteriosclerosis

The etiology of atherosclerosis is not yet fully understood, but the main risk factors include age and gender. The older the age, the higher the probability of occurrence, and the probability in men is higher than in women. Abnormal blood lipids, with the main treatment target being low-density lipoprotein, hypertension, smoking, glucose tolerance abnormalities, and obesity are all possible risk factors. Additionally, we cannot ignore family history; if there is a history of early-onset coronary heart disease in the family, then this risk factor is also very high. Moreover, personality is related, with Type A personalities being more prone to atherosclerosis. Dietary habits are also related; patients who often eat high-calorie, high-animal-fat, high-cholesterol foods are prone to develop the condition. There are also patients taking oral contraceptives, who are likely to develop atherosclerosis.

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Written by Chen Ya
Geriatrics
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How long can one live with arteriosclerosis?

Arteriosclerosis has a certain impact on survival and longevity, but it is not an absolute determinant. People with mild arteriosclerosis have fewer sudden incidents of cerebral infarction and myocardial infarction, thus they may have a longer survival period. However, if arteriosclerosis leads to myocardial infarction or cerebral infarction, it will also affect their lifespan, but there is no absolute conclusion.

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Written by Li Hai Wen
Cardiology
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Can atherosclerosis be cured?

Atherosclerosis is a very common disease in daily life. Many patients, after being diagnosed with atherosclerosis, often ask doctors "Can my atherosclerosis be cured?" The answer is no, as atherosclerosis cannot be completely cured. However, this does not mean that atherosclerosis is untreatable. From a medical perspective, controlling blood pressure, lipids, and blood sugar, maintaining good lifestyle habits, exercising regularly, quitting smoking, controlling weight, and following a doctor's guidance to properly take medications can effectively control the onset and progression of atherosclerosis.