The difference between arteriosclerosis and atherosclerosis

Written by Tang Li
Cardiology
Updated on September 26, 2024
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Arteriosclerosis is the most common and most important among a group of vascular diseases called arteriosclerosis. The common characteristics of various arteriosclerosis include thickening, hardening, loss of elasticity, and narrowing of the arterial walls. The characteristic of arteriosclerosis is that the affected arterial lesions start from the intima, with various lesions coexisting, including local accumulation of papyraceous and complex carbohydrates, proliferation of fibrous tissue, and formation of plaques due to calcification, along with gradual degradation of the arterial media. Secondary lesions include intraplaque hemorrhage, plaque rupture, and local thrombosis formation. Modern cellular and molecular biology techniques show that arteriosclerotic lesions are characterized by migration of macrophages, proliferation of smooth muscle cells, and abundant formation of fibrous, collagen, elastic fibers, and proteoglycans as connective tissue matrices, as well as intra- and extracellular lipid accumulation. Because the lipid accumulation in the intima appears yellow and mushy, it is called arteriosclerosis. Although arteriosclerosis is only one type of arteriosclerosis, it is commonly referred to simply as arteriosclerosis due to its frequent occurrence and significant clinical relevance.

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How long can one live with arteriosclerosis?

Arteriosclerosis has a certain impact on survival and longevity, but it is not an absolute determinant. People with mild arteriosclerosis have fewer sudden incidents of cerebral infarction and myocardial infarction, thus they may have a longer survival period. However, if arteriosclerosis leads to myocardial infarction or cerebral infarction, it will also affect their lifespan, but there is no absolute conclusion.

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Written by Li Hai Wen
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How to prevent arteriosclerosis

Atherosclerosis is a disease related to aging, poor lifestyle habits such as smoking, and metabolic abnormalities such as hyperlipidemia or diabetes. Atherosclerosis can be effectively prevented. To prevent atherosclerosis, the following should be adhered to: First, maintain good lifestyle habits, exercise regularly, quit smoking, limit alcohol consumption, and eat less spicy and greasy foods. Second, control blood pressure, blood lipids, and blood sugar levels. When issues such as elevated blood pressure and lipids arise, it is necessary to use medication under the guidance of a doctor.

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Written by Zeng Wei Jie
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What tests are used for arteriosclerosis?

If arteriosclerosis is in the early stages, we need to understand the situation with lipids and blood sugar, so lipid and blood glucose tests should be done. Later on, when some atheromatous plaques appear, examinations such as color Doppler ultrasound and cardiac echocardiography can be done to assess blood flow and the degree of narrowing in the vessels. For some severe narrowings, consider conducting a CTA, MRI, or angiography, which can non-invasively understand the lesions of arteriosclerosis. For some patients, if there is a need for interventional treatment, invasive, selective arterial angiography can be performed to understand the condition of the lesions. Therefore, different tests can be chosen at different stages.

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Written by Li Hai Wen
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How to check for arteriosclerosis?

Arteriosclerosis is a relatively common disease in our daily life. After being diagnosed with arteriosclerosis, the following tests should be considered: Firstly, blood tests, such as lipid panels, are necessary to determine the levels of blood lipids. Based on the results, medication might be required for treatment. Secondly, arterial Doppler ultrasound is useful as it can effectively detect the presence and severity of arteriosclerosis. Thirdly, arterial angiography is recommended when there is a strong suspicion of arterial narrowing due to arteriosclerosis, leading to coronary heart disease or other conditions. This test helps in determining the severity of the arteriosclerosis and in deciding the treatment plan.

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Is coronary arteriosclerosis serious?

The severity of arterial atherosclerosis is related to the location of the lesion and the narrowing it causes in the coronary arteries. This is because if the blood flow through the coronary arteries is insufficient to meet the metabolic demands of the heart muscle, it can lead to ischemia and hypoxia of the heart muscle, causing angina. Severe and prolonged ischemia can lead to myocardial necrosis, or myocardial infarction. When there is significant narrowing in the coronary artery lumen, for instance more than 50%-75%, the situation can be compensated during rest. However, during exercise or rapid heart rate or emotional excitation, the oxygen demand of the heart muscle increases. This may result in mild or transient myocardial oxygen supply, or an imbalance between supply and demand. Another scenario involves unstable atherosclerotic plaques that rupture, erode, or bleed, leading to platelet aggregation or thrombus formation, causing a rapid worsening of luminal narrowing. This results in a decreased supply of oxygen to heart muscle, leading to acute coronary syndrome, which is very severe. In fact, the degree of coronary artery atherosclerosis is positively correlated with plaque stability, plaque location, and the elasticity of the coronary artery.