The difference between rheumatic fever and rheumatoid arthritis

Written by Yang Ya Meng
Rheumatology
Updated on September 24, 2024
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Patients with rheumatoid arthritis primarily exhibit symmetrical swelling and pain in the small joints of both hands as the main clinical manifestations, with rarely any involvement of visceral organs. Blood tests can show elevated inflammatory markers, erythrocyte sedimentation rate (ESR), C-reactive protein, as well as positive rheumatoid factor, anti-CCP antibodies, and AK antibodies. These indicators can be considered as diagnostic for rheumatoid arthritis. Patients with rheumatic fever, in addition to joint pain, often have cardiac complications, such as mitral stenosis or chorea-like symptoms. The main difference between rheumatic fever and internal rheumatism is that patients with rheumatic fever often have cardiac complications.

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Written by Yang Ya Meng
Rheumatology
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Is rheumatic fever prone to recurrence?

Rheumatic fever recurs because it is caused by an infection with Group A streptococcus. If the streptococcus is not completely eradicated, recurrence is likely. Therefore, it is critical for patients with rheumatic fever to undergo a full course of anti-infection treatment initially. The most commonly used treatments are antibiotics such as penicillin and second-generation cephalosporins. Additionally, long-acting benzathine penicillin treatment outside the hospital is necessary to completely eradicate the streptococcus, thereby preventing the recurrent episodes of rheumatic fever. If the streptococcus is well-controlled, the likelihood of recurrence of rheumatic fever will be relatively small.

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Written by Yang Ya Meng
Rheumatology
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Treatment of rheumatic fever with aspirin

Patients with rheumatic fever use aspirin primarily for its anti-inflammatory effects to reduce the inflammatory response. Aspirin also has analgesic properties that can be used to treat symptoms like joint pain associated with rheumatic fever. However, it is crucial to monitor patients taking aspirin for any gastrointestinal reactions, such as stomach pain or black stools. During the use of aspirin, it's important to be vigilant about these gastrointestinal symptoms. Additionally, medications that protect the stomach, such as pantoprazole which reduces stomach acid, can be used to prevent the side effects of aspirin. (Use medication under the guidance of a doctor.)

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Written by Yang Ya Meng
Rheumatology
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How to treat rheumatic fever arthritis?

Rheumatic fever joint pain initially can be treated with anti-inflammatory and analgesic medications. The most commonly used are non-steroidal anti-inflammatory drugs (NSAIDs), such as slow-release diclofenac sodium tablets. Since rheumatic fever is triggered by a streptococcal infection, if the streptococcus is not controlled, joint pain may reoccur. Therefore, fundamentally, an adequate course of anti-infection treatment is also needed. In the acute phase of rheumatic fever, antibiotics such as penicillin or second-generation cephalosporins can be used for a 10-14 day treatment. Subsequently, treatment may require sequential benzathine penicillin for possibly up to six months or more than a year. (Please use medications under the guidance of a doctor.)

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Written by Du Rui Xia
Obstetrics
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Symptoms of rheumatic fever in children

Children often show symptoms of rheumatic fever, which commonly leads to myocarditis, arrhythmias, palpitations, and asthma. Additionally, there can be changes in the skin, such as subcutaneous erythema nodosum, as well as joint swelling and pain. There are also general symptoms like fever, fatigue, cough, nosebleeds, abdominal pain, nausea, and vomiting, along with swelling of the lymph nodes throughout the body. During examinations, there is often a significant increase in C-reactive protein and elevated levels of anti-streptococcal antibodies and anti-O. Abnormalities can also be seen on the electrocardiogram. Once symptoms of pediatric rheumatic fever appear, it is crucial to promptly visit a hospital for diagnosis and timely treatment.

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Written by Liu Li Ning
Rheumatology
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Rheumatic fever is not caused by a bacterium, but is a complication of a streptococcal infection.

Rheumatic fever is associated with Group A beta-hemolytic streptococcal infection and is a systemic inflammatory disease. The detailed pathogenesis is not yet very clear. Common clinical manifestations include joint pain, subcutaneous nodules, erythema marginatum, fever, chorea, and carditis. The characteristic of joint pain is that it generally does not leave joint deformities, and presents as migratory pain in the large joints of the limbs. Carditis can affect the heart valves and endocardium, primarily commonly involving the mitral or tricuspid valves. During the acute phase, penicillin antibiotics are needed for anti-infective treatment.